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Efficacy of Oleander Leaf as an Alternative Medicine According to GRADE* Ranking: WARNING: This plant is toxic! Not to be ingested. Causes nausea, appetite loss, vomiting, drowsiness, bloody diarrhoea, seizures, irregular heartbeat, heart failure, respiratory depression and death. The plant and any of its extracts should be strictly avoided, especially by children and pregnant women. Recommendation: Strongly against (There is insufficient evidence to prove the effectiveness of Oleander in the above conditions. Please note, this plant and its extracts are poisonous, even when ingested in dry form. Many people have died of heart or respiratory failure after eating parts of the plant or its extracts.) Grade of Evidence: Low level of evidence
References:
1. 1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009 2.http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/EnforcementActivitiesbyFDA/WarningLettersandNoticeofViolationLetterstoPharmaceuticalCompanies/UCM165406.pdf 3. http://www.inchem.org/documents/pims/plant/pim366.htm
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