Clostridial Soft Tissue Infections

Sign/Symptoms
Oedema (Swelling) Around Trauma or Infected Site Skin Blisters with Foul Smelling Brown Exudate Skin Cysts Filled with White Pus-like Substance Skin Discoloured around Trauma or Infection Area Skin Infection Skin Infection or Wound with Gas Bubbling

Drugs
Minocycline Piperacillin Tetracycline

Treatments
Surgery Debridement Incision and Drainage Medical Procedure Hyperbaric Oxygen Therapy (HBOT) Strongly Against Low Evidence Medical Therapy Incision and Drainage Weakly in Favour Low Evidence

Attributes

Our Records are Incomplete for Condition Attributes

Further Tests
Alpha-1 Antitrypsin (AAT) Concentration Alpha-1 Antintrypsin (AAT) (Increased) Cerebrospinal Fluid Albumin Concentration Albumin (Cerebrospinal Fluid, CSF) (Increased) Cerebrospinal Fluid Glucose Concentration Glucose (Cerebrospinal Fluid) (Decreased) Cerebrospinal Fluid Protein Concentration Cerebrospinal Fluid Total Protein (Increased) Cerebrospinal Fluid Protein Electrophoresis Prealbumin (Increased) Albumin (Cerebrospinal Fluid, CSF) (Increased) Cerebrospinal Fluid White Cell Differential Cerebrospinal Fluid Leukocytes (Increased) Cholesterol Concentration Cholesterol (Total) (Increased) Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase) Cholinesterase (Decreased) Eosinophils Count Eosinophils (Increased) erythrocyte Sedimentation Rate (ESR) Erythrocyte Sedimentation Rate (Increased) Ferritin Concentration Ferritin (Increased) Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps) Fibrin Split Products (Increased) Fibrin Monomers Test Fibrin Monomers (Increased) Fibrinopeptide A (FPA) Action Assay Fibrinopeptide A (FPA) (Increased) Glucagon Concentration Test Glucagon (Increased) Glucose 6 Phosphate Dehydrogenase (G6PD) Concentration Glucose 6 Phosphate Dehydrogenase (G6PD) (Decreased) Glucose, Blood (Fasting Blood Glucose) Glucose (Blood) (Increased) Glucose, Blood (Random Blood Glucose Test) Glucose (Blood) (Increased) haptoglobin (Hp) concentration haptoglobin (Hp) (Increased) Neutrophil Absolute Count Plasminogen Activity Plasminogen (Increased) Platelet Count Platelets (Decreased) Potassium Concentration (K, Blood) Potassium (K, Blood) (Increased) Protein Electrophoresis (Blood, Serum Protein) Alpha-1-Globulin (Blood, Serum) (Increased) Alpha-2-Globulin (Blood, Serum) (Increased) Urine glucose concentration Urine glucose (Increased) White Blood Cell (WBC) Count White Blood Cell (WBC) (Increased)

Efficacy of Alternative and Other Treatments According to GRADE* Ranking:

Hyperbaric Oxygen Therapy (HBOT):

Recommendation: weak (available evidence shows that HBOT is in no way useful in treating Clostridial infections, and can have harmful effects. NOT RECOMENDED)

Grade of Evidence: low quality of evidence

* www.gradeworkinggroup.org

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