Extrapulmonary Tuberculosis

Sign/Symptoms
Anaemia (Anemia) Breath Shortness (Dyspnoea) Chills Fatigue Fever (Raised Body Temperature) Headache (Cephalgia) Lymph Nodes Swollen (Glands) Mind: Malaise Nausea Neck Stiff Pain Abdominal Pain Pelvic Pain Whilst Breathing (Pleurisy) Pain: Chest Weakness Weight Loss (Body Mass Index Decreased)

Drugs
Amikacin Prednisolone Prednisone Streptomycin

Treatments
Surgery Debridement Resection Fistulotomy Drainage Medical Procedure Directly Observed Therapy (DOT) Isolation Vitamins Micronutrient Supplements Weakly in Favour Low Evidence Zinc No Recommendation Very Low Evidence Minerals Zinc No Recommendation Very Low Evidence Medical Therapy Directly Observed Therapy (DOT) Weakly in Favour Low Evidence Drainage Weakly in Favour Low Evidence Debridement Weakly in Favour Low Evidence Fistulotomy Weakly in Favour Low Evidence Resection Weakly in Favour Low Evidence

Attributes

Our Records are Incomplete for Condition Attributes

Further Tests
Acid Fast Bacilli (AFB Smear or Culture) Mycobacterium Tuberculosis (Increased) Alpha-1 Antitrypsin (AAT) Concentration Alpha-1 Antintrypsin (AAT) (Increased) Angiotensin Converting Enzyme (ACE) Concentration Angiotensin Converting Enzyme (ACE) (Increased) Calcium Concentration (Blood, Total) Calcium (Blood, Total) (Increased) Cerebrospinal Fluid Glucose Concentration Glucose (Cerebrospinal Fluid) (Decreased) Cholesterol Concentration Cholesterol (Total) (Increased) Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase) Cholinesterase (Decreased) Creatinine Clearance (CrCl) Creatinine Clearance Rate (Decreased) D-Dimer Blood Test D-Dimer (Increased) Fibrinogen Concentration test Fibrinogen (Increased) Fibrinopeptide A (FPA) Action Assay Fibrinopeptide A (FPA) (Increased) haptoglobin (Hp) concentration haptoglobin (Hp) (Increased) Lymphocyte Immunophenotyping CD4 to CD8 Ratio (Decreased) Lymphocytes Count Lymphocytes (Decreased) Monocyte Absolute Count Monocytes (Increased) Neutrophil Absolute Count Segmented Neutrophils (Increased) Platelet Count Platelets (Increased) Protein Electrophoresis (Blood, Serum Protein) Alpha-2-Globulin (Blood, Serum) (Increased) Tuberculin Skin Test (Mantoux Test for Tuberculosis, TB) Positive Mantoux Test (Reactive Tuberculin Test, Localized Skin Induration and Redness) (Increased) Urine glucose concentration Urine glucose (Increased) Urine Granular Cast Concentration Unrine Granular Casts (Increased) Urine Haemologlobin (Hb) Concentration Urine Haemoglobin (Hb) (Increased) Urine Leukocyte Esterase Screening Urine Leukocyte Esterase (Increased) Urine Lysozyme Concentration Lysozyme (Muramidase, Urine) (Increased) Urine pH Test Urine (Decreased) Urine Red Blood Cells Concentration Urine Red Blood Cells (Increased) Urine Urobilinogen Concentration Urobilinogen (Urine) (Increased)

Efficacy of Alternative and Other Treatments According to GRADE* Ranking:

Zinc:

Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.

Recommendation: No recommendation (There is insufficient evidence to support claims that zinc is able to help treat extrapulmonary tuberculosis. More studies needed)

Grade of Evidence: Very low quality of evidence

Micronutrient Supplements [1, 2, 3, 4]:

Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.

Recommendation: Weakly in favor (Early studies show that micronutrient supplements may be of benefit in the treatment of extrapulmonary tuberculosis)

Grade of Evidence: Low quality of evidence

* www.gradeworkinggroup.org

Summary References

Treatments:

1.http://www.merck.com/mmpe/sec14/ch179/ch179b.html?qt=Extrapulmonary%20Tuberculosis&alt=sh#sec14-ch179-ch179b-1456a

2. http://www.ncbi.nlm.nih.gov/pubmed/18471061?dopt=Abstract

3. http://www.ncbi.nlm.nih.gov/pubmed/15738377?dopt=Abstract

4. http://www.ncbi.nlm.nih.gov/pubmed/9802271?dopt=Abstract

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