Hepatocellular Carcinoma

Sign/Symptoms
Abdominal Swelling Bruising Easily Liver Enlarged Or Tender Liver: Cirrhosis Pain Abdominal Skin Yellowing (Jaundice) Weight Loss (Body Mass Index Decreased)

Drugs
Sorafenib

Attributes
Incidence is approximately 1 in 17,301 people Incidence for Third World Countries is approximately 1 in 20,661,157 people

Further Tests
Acid Phosphatase Concentration Acid Phosphatase (Increased) Activated Coagulation Time (ACT) Coagulation Bleeding Time (Increased) Activated Partial Thromboplastin Time (APTT) Plasma thromboplastin antecedent (Increased) Alpha-1 Antitrypsin (AAT) Concentration Alpha-1 Antintrypsin (AAT) (Increased) Alpha-Fetoprotein (AFP, Serum AFP, Blood) Alpha-Fetoprotein (Non-Pregnant, Serum) (Increased) Ammonia Concentration Test Ammonia (Increased) Ammonia (Increased) Apolipoprotein A Concentration Apolipoprotein A (Apo A) (Decreased) Apolipoprotein B Concentration Apolipoprotein B (Apo B) (Increased) Aspartate Aminotransferase (AST) Concentration Aspartate Aminotransferase (AST) (Increased) Blood Uric Acid Concentration Test Uric Acid, Blood (Decreased) Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase) Cholinesterase (Decreased) Coagulation Factor Assay (Blood Clotting Factors) Factor X (Stuart Prower Factor, Percentage of Normal Value) (Decreased) Factor IX (Christmas Factor, Percentage of Normal Value) (Decreased) Factor V (Labile Factor, Proaccelerin, Percentage of Normal Value) (Decreased) Creatine Kinase Concentration Creatine Kinase (CK) (Decreased) D-Dimer Blood Test D-Dimer (Increased) Fecal Urobilinogen Concentration Urobilinogen (Stools) (Decreased) Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps) Fibrin Split Products (Increased) Fibrin Monomers Test Fibrin Monomers (Increased) Fibrinogen Concentration test Fibrinogen (Decreased) Fibrinopeptide A (FPA) Action Assay Fibrinopeptide A (FPA) (Increased) Gamma-Glutamyltransferase (GGT) Concentration Gamma-Glutamyltransferase (GGT) (Increased) haptoglobin (Hp) concentration haptoglobin (Hp) (Increased) High Density Lipoprotein (HDL) Concentration High Density Lipoprotein (HDL) (Decreased) Lactate Dehydrogenase Concentration Lactate Dehydrogenase (LDH) (Increased) lipase concentration Lipase (Increased) Low Density Lipoprotein (LDL) Concentration Low Density Lipoprotein (LDL) (Increased) Mean Corpuscular Volume (MCV) Red Blood Cell (RBC) Volume (Decreased) Phenylketonuria Test Phenylalanine (Increased) Plasminogen Activity Plasminogen (Decreased) Potassium Concentration (K, Blood) Potassium (K, Blood) (Decreased) Protein Electrophoresis (Blood, Serum Protein) Albumin (Blood) (Decreased) Alpha-1-Globulin (Blood, Serum) (Increased) Alpha-2-Globulin (Blood, Serum) (Increased) Gamma Globulin (Blood, Serum) (Increased) Prothrombin Time (PT) Prothrombin Time (Increased) Thyroglobulin (Tg) Concentration Thyroglobulin (Tg) (Increased) Urine Sodium Quantitative (24hr) Urine Sodium (Decreased) Vitamin B12 (VB12) Concentration Vitamin B12 (VB12) (Increased)

Summary References

Treatments:

1. http://www.merck.com/mmpe/sec03/ch029/ch029d.html#sec03-ch029-ch029d-600a

2. Chen, Min-Shan; Li, Jin-Qing; Zheng, Yun; Guo, Rong-Ping; Liang, Hui-Hong; Zhang, Ya-Qi; Lin, Xiao-Jun; Lau, Wan Y (2006). "A Prospective Randomized Trial Comparing Percutaneous Local Ablative Therapy and Partial Hepatectomy for Small Hepatocellular Carcinoma". Annals of Surgery 243 (3): 321–8.

3. American Society of Clinical Oncology, 2005 Annual Meeting, Abstracts on Hepatobiliary Cancer

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