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WARNING! This substance is HIGHLY POISONOUS. The seeds contain Strychnine, which may cause convulsions, breathing difficulties and death, even if as little as 5 milligrams is ingested
Recommendation: Strongly against (There is no evidence in the form of clinical trials which report the effectiveness of Strychnos Nux-Vomica, because it is highly poisonous to humans, and is not recommended.)
Grade of Evidence: very low quality of evidence
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: weakly in favor (Laboratory studies show that rabdosia rubescens has anti-cancer activity, and may be helpful in the treatment of liver cancer. However, more studies are needed)
Grade of Evidence: low quality of evidence
Please note, this treatment has potentially serious side effects. Some of the chemicals in the plant are known to be toxic. High doses are known to cause liver and kidney. Even at low doses, chemicals in the plant may interfere with blood clotting, causing excess bleeding and anaemia. Pau D'Arco should be avoided, especially by pregnant or breastfeeding women.
Recommendation: Strongly against (Laboratory tests have shown that Pau D'arco can be effective in the treatment of liver cancer. However, further studies are needed on its effect in humans. This, combined with its potentially harmful side effects if taken without supervision from a doctor or pharmacist gives enough reason to avoid this treatment.)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/pau-d-arco
3. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?fs=ND&pt=100&id=1140&AspxAutoDetectCookieSupport=1
4. http://mct.aacrjournals.org/content/4/4/578.abstract
5. http://www.ncbi.nlm.nih.gov/pubmed/15586232
6. http://www.webmd.com/vitamins-supplements/ingredientmono-1140-RABDOSIA RUBESCENS.aspx?activeIngredientId=1140&activeIngredientName=RABDOSIA RUBESCENS
7. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/rabdosia-rubescens
8. http://alternativehealing.org/dong_ling_cao.htm
9. David Michael Wood et al. Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data. Critical Care October 2002 Vol 6 No 5
10. Arnold, M.D., Harry L. (1968). Poisonous Plants of Hawaii. Tokyo, Japan: Charles E. Tuttle Co.. p. 20. ISBN 0804804745.
11. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/strychnos-nux-vomica