Peripheral Arterial Disease

Efficacy of Alternative and Other Treatments According to GRADE* Ranking:

Strychnos Nux-Vomica (Maqianzi, Poison Nut) [1, 8, 9, 10]:

WARNING! This substance is HIGHLY POISONOUS. The seeds contain Strychnine, which may cause convulsions, breathing difficulties and death, even if as little as 5 milligrams is ingested

Recommendation: Strongly against (There is no evidence in the form of clinical trials which reports the effectiveness of Strychnos Nux-Vomica, because it is highly poisonous to humans, and is not recommended.)

Grade of Evidence: very low quality of evidence

Megavitamin Therapy (Multivitamin, Vitamin Supplements) [1, 2, 3, 4, 5, 6, 7]:

Please Note that while supplements are effective in correcting deficiencies in the body, their long-term usage is not helpful in preventing diseases like cancer and heart disease. To prevent these illnesses one should eat the natural foods which these vitamins and minerals come from. Replacing natural sources with artificial supplements actually increases the risk of heart disease, cancer, and other diseases. Supplements should be taken only as a balanced multivitamin supplement that contains no more than 100% of the recommended daily allowance. It would be most helpful in people with restricted food intakes, pregnant women and women of childbearing age.

Recommendation: Weakly against. (There is no evidence that Megavitamin therapy can prevent or treat peripheral arterial disease. In fact, long term therapy can lead to increased risk)

Grade of Evidence: moderate quality of evidence

Tai Chi:

Recommendation: weakly in favor (Available evidence shows that Tai Chi may have cardiovascular benefits, which include reducing symptoms of peripheral arterial disease)

Grade of Evidence: low quality of evidence

* www.gradeworkinggroup.org

Summary References

Treatments:

1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/orthomolecular-medicine

3. http://archpedi.ama-assn.org/cgi/reprint/163/2/192.pdf

4. http://www.quackwatch.org/01QuackeryRelatedTopics/ortho.html

5. http://pediatrics.aappublications.org/cgi/content/abstract/72/5/707

6. http://www.ama-assn.org/ama/no-index/about-ama/13638.shtml

7. http://www.ncbi.nlm.nih.gov/pubmed/17327526

8. David Michael Wood et al. Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data. Critical Care October 2002 Vol 6 No 5

9. Arnold, M.D., Harry L. (1968). Poisonous Plants of Hawaii. Tokyo, Japan: Charles E. Tuttle Co.. p. 20. ISBN 0804804745.

10. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/strychnos-nux-vomica



 

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