Erythrocyte Fragility Test (Osmotic Fragility, OF)

Reference Ranges

Percentage NaCl at which Hemolysis begins

All

0.50 TO 0.60 %

Percentage NaCl at which Hemolysis is complete

All

0.30 TO 0.35 %

Conditions
Hemolytic Anemia Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) Traumatic Hemolytic Anemia Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) Autoimmune Hemolytic Anemia Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) Hereditary Spherocytosis Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) ABO Hemolytic Disease of the Newborn Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) Anti-Kell Hemolytic Disease of the Newborn Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) Pyruvate Kinase Deficiency Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) Malaria Percentage NaCl at which Hemolysis begins (Increased) Percentage NaCl at which Hemolysis is complete (Increased) Hemoglobin S Beta Thalassemia Disease Percentage NaCl at which Hemolysis begins (Decreased) Percentage NaCl at which Hemolysis is complete (Decreased) Thalassemias Percentage NaCl at which Hemolysis begins (Decreased) Percentage NaCl at which Hemolysis is complete (Decreased) Hemoglobin C Disease Percentage NaCl at which Hemolysis begins (Decreased) Percentage NaCl at which Hemolysis is complete (Decreased) Hemoglobin S C Disease Percentage NaCl at which Hemolysis begins (Decreased) Percentage NaCl at which Hemolysis is complete (Decreased) Iron Deficiency Percentage NaCl at which Hemolysis begins (Decreased) Percentage NaCl at which Hemolysis is complete (Decreased) Iron Deficiency Anemia Percentage NaCl at which Hemolysis begins (Decreased) Percentage NaCl at which Hemolysis is complete (Decreased) Reticulocytosis Percentage NaCl at which Hemolysis begins (Decreased) Percentage NaCl at which Hemolysis is complete (Decreased) Hemolytic Uremic Syndrome Percentage NaCl at which Hemolysis is complete (Increased)

Summary References

Treatments:

1. http://www.calgarylabservices.com/LabTests/AlphabeticalListing/O/Osmotic-Fragility-Erythrocyte.htm

2. http://www.scribd.com/doc/4762150/ERYTHROCYTE-FRAGILITY-TEST

3. http://medical-dictionary.thefreedictionary.com/erythrocyte+fragility+test

4. http://www.medicine.mcgill.ca/physio/vlab/bloodlab/eryfrag3_n.htm

5. http://www.drugs.com/dict/erythrocyte-fragility-test.html

6. http://www.biology-online.org/dictionary/Fragility_test

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