Hyperlipidemia

Sign/Symptoms
Angina Chest Pain Cholesterol Decrease HDL Cholesterol Increased LDL Eyelid: Yellowish Growth Under Skin around Eyelids (Xanthelasma - Cholestrol Deposits) Obesity Xanthoma (Fat Deposits Under Skin over Joints and Tendons)

Drugs
Fenofibrate Simvastatin

Treatments
Vitamins Selenium Supplementation No Recommendation Very Low Evidence Minerals Selenium Supplementation No Recommendation Very Low Evidence

Attributes
Commonality is common

Further Tests
amylase concentration Amylase (Increased) Apolipoprotein B Concentration Apolipoprotein B (Apo B) (Decreased) Cholesterol Concentration Cholesterol (Total) (Increased) Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase) Cholinesterase (Increased) Glucagon Concentration Test Glucagon (Increased) Glucose Tolerance Test (GTT, OGTT, 120 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, 160 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, 30 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, 60 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, Fasting Glucose) Glucose (Blood) (Increased) Glucose Tolerance Test for Gestational Diabetes (1 Hour After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test for Gestational Diabetes (Fasting Glucose Value) Glucose (Blood) (Increased) Glucose, Blood (Fasting Blood Glucose) Glucose (Blood) (Increased) Glucose, Blood (Random Blood Glucose Test) Glucose (Blood) (Increased) Low Density Lipoprotein (LDL) Concentration Low Density Lipoprotein (LDL) (Increased) Triglyceride (TGs) Concentration Triglycerides (Increased) Urine Amylase Excretion Rate Urine Amylase (Increased)

Efficacy of Alternative and Other Treatments According to GRADE* Ranking:

Selenium Supplement [1, 2, 3, 4, 5, 6, 7, 8, 9, 10]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. IMPORTANT: Selenium is toxic in high doses. Massive overdoses can cause kidney failure, breathing difficulty and death. Selenium should only be taken at healthy levels which the body is able to tolerate.

Recommendation: No recommendation (Available evidene does not support claims that selenium helps to prevent or treat hyperlipidemia)

Grade of Evidence: very low quality of evidence

* www.gradeworkinggroup.org

Summary References

Treatments:

1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/selenium?sitearea=ETO

3. http://www.cancer.gov/Templates/doc.aspx?viewid=ED8AD8E8-6AE5-458D-8091-393F4CB73F0D

4. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-selenium.html

5. http://www.ncbi.nlm.nih.gov/pubmed/9290116

6. http://www.ncbi.nlm.nih.gov/pubmed/9829869

7. http://www.ncbi.nlm.nih.gov/pubmed/10335455

8. http://www.ncbi.nlm.nih.gov/pubmed/2136228

9. http://www.springerlink.com/content/v0r644v4ju5153k2/

10. http://jnci.oxfordjournals.org/cgi/content/full/101/5/283

11. http://www.nlm.nih.gov/medlineplus/ency/article/000396.htm

12. http://www.healinglightseminars.com/listing/Hyperlipidemia.pdf

13. http://www.netdoctor.co.uk/ate/diabetes/202338.html

14. http://healthy-ojas.com/cholesterol/cholesterol-details.html

15. http://img.thebody.com/legacyAssets/27/77/hyperlipidemia.pdf

16. http://www.healthscout.com/ency/68/366/main.html

17. http://www.uptodate.com/patients/content/topic.do?topicKey=~6jxGpYRK1ieFx

18. http://medical-dictionary.thefreedictionary.com/hyperlipidemia

19. http://www.vascularweb.org/vascularhealth/Pages/Hyperlipidemia.aspx

20. http://healthcenter.ucdavis.edu/topics/hyperlipidemia.html

21. http://www.thewellproject.org/en_US/Diseases_and_Conditions/Treatment_Related_Conditions/Hyperlipidemia.jsp

22. http://www.ncbi.nlm.nih.gov/pubmed/2192873

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