Selenium Supplementation

Identification
Generic Name
Selenium Supplementation
Brand Name

 

Indication

Condition Contra-Indication
Our Records are Incomplete for Condition-Contra Indications

 
Other Contra-Indication
Our Records are Incomplete for Other Contra-Indications

Contra-Indication
Our Records are Incomplete for Drug Contra-Indications

 
Class Contra-Indication
Our Records are Incomplete for Drug Class Contra-Indications

We have incomplete side-effect data.

Side Effects

Efficacy of Selenium Supplementation as an Alternative Medicine According to GRADE* 

Recommendation: No recommendation (There is insufficient evidence to support claims that selenium supplementation helps to treat hepatitis, goiter, thyroiditis, hyperthyroidism, hypothyroidism, acute coronary syndromes, pancreatitis, asthma, hypercholesterolaemia, prostate cancer, heart disease, hyperlipidemia. More research is needed.)

Grade of Evidence: Very low level of evidence


Ovarian Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent ovarian cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


Alzheimer's Disease [10, 11, 12]:

Recommendation: Weakly in Favor (Current evidence does not indicate it is an effective treatment for AD but some evidence shows selenium to be an effective preventive strategy for the development of AD, however it is likely to be useful in conjunction with other treatments)

Grade of Evidence: Very low level of evidence

 

Bladder Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent bladder cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


Breast Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent breast cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


Esophageal Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent esophageal cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


Pancreatic Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent pancreatic cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


Colon Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent colon cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


Colorectal Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent colorectal cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


Lung Cancer [1, 2, 3, 4, 5, 6, 7, 8, 9]:

Recommendation: Weakly in favor (Observational studies have shown that taking adequate daily amounts of selenium can help prevent lung cancer. However, these are very unreliable studies, and more research is needed.)

Grade of Evidence: Very low level of evidence


* www.gradeworkinggroup.org 

References: 

1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

2. http://www.cancer.gov/Templates/doc.aspx?viewid=ED8AD8E8-6AE5-458D-8091-393F4CB73F0D

3. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-selenium.html

4. http://www.ncbi.nlm.nih.gov/pubmed/9290116

5. http://www.ncbi.nlm.nih.gov/pubmed/9829869

6. http://www.ncbi.nlm.nih.gov/pubmed/10335455

7. http://www.ncbi.nlm.nih.gov/pubmed/2136228

8. http://www.springerlink.com/content/v0r644v4ju5153k2/

9. http://jnci.oxfordjournals.org/cgi/content/full/101/5/283

10. http://www.ncbi.nlm.nih.gov/pubmed/22536767

11. http://www.ncbi.nlm.nih.gov/pubmed/17272290

12. http://www.ncbi.nlm.nih.gov/pubmed/15207438



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