Hypercholesterolaemia

Sign/Symptoms
Drugs
Treatments
Attributes
Commonality is common
Further Tests

Efficacy of Alternative and Other Treatments According to GRADE* Ranking:

Vitamin E [1, 46, 47, 48, 49, 50, 51]:

Please note, this management does NOT treat the condition itself. It may mildly help in preventing some of the symptoms, and even then has insufficient evidence to back up this claim at present. Please note, this acts as a PREVENTATIVE treatment, and not necessarily symptomatic relief.  This vitamin can have harmful effects if taken in doses higher than 100% of the recommended daily allowance.

Recommendation: No recommendation (There is insufficient evidence to support claims that vitamin E supplements can help to prevent or treat hypercholestrolemia)

Grade of Evidence: very low quality of evidence

Turmeric [1, 40, 41, 42, 43, 44, 45]:

Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.

Recommendation: Weakly in favor (Early laboratory studies show that turmeric may be of benefit in the treatment of hypercholestrolemia. However, further studies are needed)

Grade of Evidence: low quality of evidence

Selenium Supplement [1, 31, 32, 33, 34, 35, 36, 37, 38, 39]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. IMPORTANT: Selenium is toxic in high doses. Massive overdoses can cause kidney failure, breathing difficulty and death. Selenium should only be taken at healthy levels which the body is able to tolerate.

Recommendation:  No recommendation (Available evidene does not support claims that selenium helps to prevent or treat hypercholestrolemia)

Grade of Evidence: very low quality of evidence

Psyllium (Isphagula, Plantago Psyllium) [1, 25, 26, 27, 28, 29, 30]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.

Recommendation: strongly in favor (Clinical trials have shown that Psyllium is effective in treating hypercholestrolemia)

Grade of Evidence: high quality of evidence

Pine Bark Extract [1, 22, 23, 24]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.

Recommendation: weakly in favor  (Early studies indicate potential for Pine bark extract in the treatment of hypercholestrolemia, but more clinical studies need to be done)

Grade of Evidence: low quality of evidence

Licorice (Glcyrhiz Gaba) [1, 18, 19, 20, 21]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. Licorice has been shown to have potentially harmful side effects in people with high blood pressure, liver or kidney diseases)

Recommendation: No recommendation (There is insufficient evidence to support claims that licorice helps treat hypercholestrolemia. More research is needed)

Grade of Evidence: very low quality of evidence

Green Tea [1, 13, 14, 15, 16, 17]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.

Recommendation: Weakly in favor (There is insufficient evidence to support claims that Green Tea helps to treat hypercholestrolemia in any way. Although reports are positive, more studies are needed.)

Grade of Evidence: low quality of evidence

Glyconutrients [1, 11, 12]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.

Recommendation: no recommendation  (Available evidence does not support claims that glyconutrients help to treat hypercholestrolemia. More studies are needed.)

Grade of Evidence: low quality of evidence

Flaxseed Oil  [1, 8, 9, 10]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.

Recommendation: no recommendation  (There is insufficient evidence to support claims that flaxseed oil helps to treat hypercholesterolemia)

Grade of Evidence: low quality of evidence

Evening Primrose Oil  [1, 5, 6, 7]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.

Recommendation: no recommendation  (There is insufficient evidence to support claims that Primrose Oil helps to treat hypercholestrolemia any way.)

Grade of Evidence: very low quality of evidence

Chlorella (Green Algae, Chlorella Pyrenoidosa) [1, 2, 3, 4]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.

Recommendation: weakly in favor  (Small studies have suggested possible benefits in treating hypercholestrolemia, but more research is needed)

Grade of Evidence: low quality of evidence

Red Pepper (Capsaicin):

Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.

Recommendation: no recommendation (There is insufficient evidence to support claims that red peppers help to treat or prevent hypercholestrolemia)

Grade of Evidence: very low quality of evidence

Black Walnut (Juglans Nigra):

Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.

Recommendation: weakly in favor (Available evidence supports claims that walnut helps to treat hypercholestrolemia, but more study is needed)

Grade of Evidence: low quality of evidence

Yoga:

Recommendation: weakly in favor (research has shown that Yoga can help to treat Hypercholesterolaemia)

Grade of Evidence: low quality of evidence

Qigong:

Recommendation: weakly in favor (reports demonstrate that Qigong can help to treat Hypercholesterolaemia)

Grade of Evidence: low quality of evidence

Meditation:

Recommendation: no recommendation (there is insufficient evidence that shows that Meditation helps to treat Hypercholesterolaemia)

Grade of Evidence: very low quality of evidence

Alfalfa Seeds [52, 53]:

Alfalfa leaves are safe for most adults. But taking alfalfa seeds long-term is may be unsafe. Alfalfa seed products may cause reactions that are similar to the autoimmune disease called lupus erythematosus.  Alfalfa might also cause some people's skin to become extra sensitive to the sun. Wear sunblock outside, especially if you are light-skinned.

Recommendation: weakly in favour (Available evidence supports claims that alfala seeds help to treat hypercholestrolemia, but more study is needed)

Grade of evidence: low quality of evidence

 

* www.gradeworkinggroup.org

 

Summary References

Treatments:

1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

2. Nakano, S et al. “Maternal-fetal distribution and transfer of dioxins in pregnant women in Japan, and attempts to reduce maternal transfer with Chlorella (Chlorella pyrenoidosa) supplements...” Chemosphere 2005 Dec; 61(9): 1244–55.

3. http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11347287&dopt=Abstract

4. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/chlorella

5. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/evening-primrose

6. http://nccam.nih.gov/health/eveningprimrose/

7. http://news.bbc.co.uk/2/hi/health/4395826.stm

8. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/flaxseed

9. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-flaxseed.html

10. http://nccam.nih.gov/health/flaxseed/index.htm

11. http://abcnews.go.com/2020/story?id=3228488

12. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/glyconutrients

13. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/green-tea

14. http://www.ncbi.nlm.nih.gov/pubmed/16968850

15.  http://www.denverpost.com/nationworld/ci_4326770

16. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-green_tea.html

17. http://nccam.nih.gov/health/greentea/index.htm

18. Winston, David; Steven Maimes (2007). Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Healing Arts Press.

19. http://www.ncbi.nlm.nih.gov/pubmed/15190039

20. http://nccam.nih.gov/health/licoriceroot/

21. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-licorice.html

22. http://www.clinicaltrials.gov/ct/show/NCT00214032

23. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/pine-bark-extract

24. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-pycnogenol.html

25. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-psyllium.html

26. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a601104.html

27. http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cmed&part=A17913

28. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/psyllium

29. http://www.mayoclinic.com/health/cholesterol-lowering-supplements/CL00013/METHOD=print

30. http://www.ageless.co.za/herb-psyllium.htm

31. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/selenium?sitearea=ETO

32. http://www.cancer.gov/Templates/doc.aspx?viewid=ED8AD8E8-6AE5-458D-8091-393F4CB73F0D

33. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-selenium.html

34. http://www.ncbi.nlm.nih.gov/pubmed/9290116

35. http://www.ncbi.nlm.nih.gov/pubmed/9829869

36. http://www.ncbi.nlm.nih.gov/pubmed/10335455

37. http://www.ncbi.nlm.nih.gov/pubmed/2136228

38. http://www.springerlink.com/content/v0r644v4ju5153k2/

39. http://jnci.oxfordjournals.org/cgi/content/full/101/5/283

40. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/turmeric

41. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-turmeric.html

42. http://nccam.nih.gov/health/turmeric/index.htm

43. http://news.bbc.co.uk/2/hi/health/1668932.stm

44. http://www.mirror.co.uk/news/top-stories/2009/10/28/curry-kills-cancer-cells-and-other-health-benefits-of-the-nations-favourite-dish-115875-21779950/

45. http://clinicaltrials.gov/ct2/results?term=turmeric

46. http://nccam.nih.gov/news/alerts/vitamine/vitamine.htm

47. http://nccam.nih.gov/research/results/spotlight/070106.htm

48. http://www.nlm.nih.gov/medlineplus/vitamine.html

49. http://www.ajcn.org/cgi/content/full/76/4/703

50. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586922/?tool=pmcentrez

51. http://ods.od.nih.gov/factsheets/vitamine.asp#h3

52. http://ncbi.nlm.nih.gov/pubmed/3606731

53. http://ncbi.nlm.nih.gov/pubmed/7379953














 


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