Pine Bark

Identification
Generic Name
Pine Bark
Brand Name

 

Indication

Condition Contra-Indication
Our Records are Incomplete for Condition-Contra Indications

 
Other Contra-Indication
Our Records are Incomplete for Other Contra-Indications

Contra-Indication
Our Records are Incomplete for Drug Contra-Indications

 
Class Contra-Indication
Our Records are Incomplete for Drug Class Contra-Indications

We have incomplete side-effect data.

Side Effects
Efficacy of Pine Bark as an Alternative Medicine According to GRADE* Ranking: 


Diabetes Mellitus [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat diabetes)

Grade of Evidence: Very low level of evidence


Erectile Dysfunction [4, 5]:

Recommendation: Weakly in Favor (Studies show that pine bark may be able to help treat those with erectile dysfunction)

Grade of Evidence: Low level of Evidence


Osteoarthritis Erosive [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat arthritis)

Grade of Evidence: Very low level of evidence


Period Pain (Dysmenorrhea) [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of dysmenorrhea, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Stroke [1, 2, 3]:

Recommendation: Weakly in favor  (Early studies indicate potential for Pine bark extract in the treatment of strokes, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Venous Thromboembolism [1, 2, 3]:

Recommendation: Weakly in favor  (Early studies indicate potential for Pine bark extract in the treatment of Venous Thromboembolism, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Acute Coronary Syndromes [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of coronary disease, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Acute Stress Disorder [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat stress)

Grade of Evidence: Very low level of evidence


Angina [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of angina, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Angina  Pectoris [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of angina, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Asthma [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of asthma, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Chronic Venous Insufficiency [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of chronic venous insufficiency, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Diabetes Type 1 [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat diabetes)

Grade of Evidence: Very low level of evidence


Diabetes Type 2 [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat diabetes)

Grade of Evidence: Very low level of evidence


Diabetic Nephropathy [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat diabetes)

Grade of Evidence: Very low level of evidence


Diabetic Retinopathy [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of diabetic retinopathy, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Hypercholesterolaemia [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of hypercholestrolemia, but more clinical studies need to be done)

Grade of Evidence: Low quality of evidence


Ischemic Stroke [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of strokes, but more clinical studies need to be done)

Grade of Evidence: Low quality of evidence


Lymphedema [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of lymphedema, but more clinical studies need to be done)

Grade of Evidence: Low quality of evidence


Occupational Asthma [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of asthma, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Osteoarthritis [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat osteoarthritis)

Grade of Evidence: Very low level of evidence


Poststreptococcal Reactive Arthritis [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat osteoarthritis)

Grade of Evidence: Very low level of evidence


Premenstrual Syndrome [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of PMS, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Reactive Arthritis [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat osteoarthritis)

Grade of Evidence: Very low level of evidence


Rheumatoid Arthritis [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat osteoarthritis)

Grade of Evidence: Very low level of evidence


Variant Angina [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of angina, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Varicose Veins [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of varicose veins, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Myocardial Infarction [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of infarction, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Coronary Heart Disease [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of heart disease, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Cerebrovascular Disease (Stroke) [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of strokes, but more clinical studies need to be done)

Grade of Evidence: Low quality of evidence


Acute Stress Reaction [1, 2, 3]:

Recommendation: No recommendation (There is insufficient evidence to support claims that Pine Bark extract helps to treat stress)

Grade of Evidence: Very low level of evidence


Ischaemic Heart Disease [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of heart disease, but more clinical studies need to be done)

Grade of Evidence: Low quality of evidence


Unstable Angina [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of angina, but more clinical studies need to be done)

Grade of Evidence: Low level of evidence


Familial Hypercholesterolaemia [1, 2, 3]:

Recommendation: Weakly in favor (Early studies indicate potential for Pine bark extract in the treatment of hypercholestrolemia, but more clinical studies need to be done)

Grade of Evidence: Low quality of evidence


* www.gradeworkinggroup.org 

References: 
1.  Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

2. http://www.clinicaltrials.gov/ct/show/NCT00214032

3. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-pycnogenol.html

4. http://menfertility.org/pine-bark-extract-benefits-male-fertility-study/

5. http://www.drugs.com/npp/maritime-pine.html


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