Hyperthyroidism

Sign/Symptoms
Appetite Loss (Anorexia) Blood: Abnormal Thyroid Hormone Level Blood: Thyroid Hormone Low (Hypothyroidism) Diarrhoea (Diarrhea) Heartbeats Felt By Patient (Palpitations) Nausea Nausea: Dry Heaves Vomiting Vomiting Blood (Hematemesis) Weight Loss (Body Mass Index Decreased)

Drugs
Carbimazole

Treatments
Surgery Thyroidectomy Medical Procedure Radioiodine Therapy Iodine Vitamins Selenium Supplementation No Recommendation Very Low Evidence Minerals Selenium Supplementation No Recommendation Very Low Evidence Medical Therapy Iodine Weakly in Favour Low Evidence Radioiodine Therapy Weakly in Favour Low Evidence Thyroidectomy Weakly in Favour Low Evidence

Attributes

Our Records are Incomplete for Condition Attributes

Further Tests
2,3 Diphosphoglycerate (2,3-DPG) Concentration 2,3 Diphosphoglycerate (2,3-DPG) (Increased) Angiotensin Converting Enzyme (ACE) Concentration Angiotensin Converting Enzyme (ACE) (Increased) Apolipoprotein B Concentration Apolipoprotein B (Apo B) (Decreased) Calcium Concentration (Blood, Total) Calcium (Blood, Total) (Increased) Coagulation Factor Assay (Blood Clotting Factors) Factor VIII (Antihemophilic Globulin, Percentage of Normal Value) (Increased) Creatinine Concentration (Blood, Serum Creatinine) Creatinine (Blood) (Increased) Ferritin Concentration Ferritin (Increased) Fetal Hemoglobin (Hemoglobin F, HbF) Concentration Fetal Hemoglobin (Hemoglobin F, HbF) (Increased) Folic Acid (Folate) Concentration Folic Acid (Folate) (Decreased) Glucose 6 Phosphate Dehydrogenase (G6PD) Concentration Glucose 6 Phosphate Dehydrogenase (G6PD) (Increased) Glucose Tolerance Test (GTT, OGTT, 120 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, 160 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, 30 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, 60 Minutes After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test (GTT, OGTT, Fasting Glucose) Glucose (Blood) (Increased) Glucose Tolerance Test for Gestational Diabetes (1 Hour After Glucose Load) Glucose (Blood) (Increased) Glucose Tolerance Test for Gestational Diabetes (Fasting Glucose Value) Glucose (Blood) (Increased) Glucose, Blood (Fasting Blood Glucose) Glucose (Blood) (Increased) Glucose, Blood (Post Prandiol Blood Glucose Test, 2 Hour Post Meal Blood Glucose) Glucose (Blood) (Increased) Hemoglobin (Hb) A2 Concentration Hemoglobin (Hb) A2 (Increased) High Density Lipoprotein (HDL) Concentration High Density Lipoprotein (HDL) (Decreased) Lymphocytes Count Lymphocytes (Increased) Phosphate Concentration (PO4, Phosphorus) Phosphate (PO4, Phosphorus, P) (Increased) Protein Electrophoresis (Blood, Serum Protein) Albumin (Blood) (Decreased) Alpha-1-Globulin (Blood, Serum) (Decreased) Alpha-2-Globulin (Blood, Serum) (Decreased) Testosterone Concentration Testosterone (Increased) Thyroid Stimulating Horomone (TSH) Concentration Thyroid Stimulating Horomone (TSH) (Decreased) Thyroxine (Free T4) Concentration Thyroxine Index (Free T4) (Increased) Thyroxine (Total T4) Concentration Thyroxine (Total T4) (Increased) Thyroxine (Total T4) (Increased) Thyroxine Binding Globulin Concentration (TBG, Thyroid Binding Globulin, Blood) Thyroxine Binding Globulin (TBG, Thyroid Binding Globulin, Blood) (Decreased) Triglyceride (TGs) Concentration Triglycerides (Decreased) Triiodothyronine (Free T3) Concentration Triiodothyronine (Free T3) (Increased) Triiodothyronine (Total T3) Concentration Triiodothyronine (Total T3) (Increased) Triiodothyronine (Total T3) (Increased) Triiodothyronine Uptake Test Triiodothyronine Uptake Percentage (Increased) Urine Amylase Excretion Rate Urine Amylase (Decreased) Urine bilirubin Concentration Urine bilirubin (Increased) Urine Chloride Concentration Urine Chloride (Increased) Urine Estradiol (E2) Concetration Urine Estradiol (E2) (Increased) Urine Hydroxyproline Concentration Hydroxyproline (Urine Excretion Rate) (Increased) Urine Ketone Concentration Urine Ketone (Increased)

Efficacy of Alternative and Other Treatments According to GRADE* Ranking:

Selenium Supplement [3, 4, 5, 6, 7, 8, 9, 10, 11, 12]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. IMPORTANT: Selenium is toxic in high doses. Massive overdoses can cause kidney failure, breathing difficulty and death. Selenium should only be taken at healthy levels which the body is able to tolerate.

Recommendation: No recommendation (Available evidene does not support claims that selenium helps to prevent or treat any thyroid conditions)

Grade of Evidence: very low quality of evidence

Black Walnut (Juglans Nigra):

Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.

Recommendation: weakly against (Available evidence does not support claims that Black Walnut helps to treat hyperthyroidism)

Grade of Evidence: low quality of evidence

* www.gradeworkinggroup.org

Summary References

Treatments:

1. Esfahani AF, Kakhki VR, Fallahi B, et al. (2005). "Comparative evaluation of two fixed doses of 185 and 370 MBq 131I, for the treatment of Graves' disease resistant to antithyroid drugs". Hellenic Journal of Nuclear Medicine 8 (3): 158–61

2. http://www.merck.com/mmpe/sec12/ch152/ch152e.html?qt=Hyperthyroidism&alt=sh#sec12-ch152-ch152e-272

3. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

4. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/selenium?sitearea=ETO

5. http://www.cancer.gov/Templates/doc.aspx?viewid=ED8AD8E8-6AE5-458D-8091-393F4CB73F0D

6. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-selenium.html

7. http://www.ncbi.nlm.nih.gov/pubmed/9290116

8. http://www.ncbi.nlm.nih.gov/pubmed/9829869

9. http://www.ncbi.nlm.nih.gov/pubmed/10335455

10. http://www.ncbi.nlm.nih.gov/pubmed/2136228

11. http://www.springerlink.com/content/v0r644v4ju5153k2/

12. http://jnci.oxfordjournals.org/cgi/content/full/101/5/283

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