Vitamin D3

Identification
Generic Name Vitamin D3
Brand Name

Indication
Bipolar Disorder No Recommendation Very Low Evidence Diabetes Mellitus No Recommendation Very Low Evidence Hereditary Vitamin D Dependent Rickets Strongly in Favour High Evidence Schizophrenia No Recommendation Very Low Evidence Alzheimers Disease Weakly in Favour Very Low Evidence Anorexia Nervosa Weakly in Favour Low Evidence Childhood Schizophrenia No Recommendation Very Low Evidence Chronic Renal Failure Strongly in Favour Moderate Evidence Cystic Fibrosis Weakly in Favour Low Evidence Depression No Recommendation Very Low Evidence Diabetes Type 1 No Recommendation Very Low Evidence Familial Adenomatous Polyposis Weakly in Favour Low Evidence Herniated Nucleus Pulposus No Recommendation Very Low Evidence Obesity No Recommendation Very Low Evidence Osteoporosis Strongly in Favour High Evidence Prostate Cancer Weakly in Favour Low Evidence Psoriasis Strongly in Favour High Evidence Hip Fracture Strongly in Favour High Evidence Colorectal Cancer Weakly in Favour Low Evidence Rickets Strongly in Favour High Evidence Autism No Recommendation Very Low Evidence Major Depressive Disorder No Recommendation Very Low Evidence

Condition Contra-Indication
Our Records are Incomplete for Condition-Contra Indications

Other Contra-Indication

Our Records are Incomplete for Other Contra-Indications

Contra-Indication
Our Records are Incomplete for Drug Contra-Indications

Class Contra-Indication

Our Records are Incomplete for Drug Class Contra-Indications

We have incomplete side-effect data.

Side Effects

Efficacy of Vitamin D3 as an Alternative Medicine According to GRADE* Ranking:

Hereditary Vitamin D Dependent Rickets [1, 2, 3, 5, 7]:

Recommendation: Strongly in favor (Studies have shown that a Vitamin D can help to prevent and treat rickets)

Grade of Evidence: High level of evidence

Anorexia Nervosa [1, 5, 7, 8, 9, 10]:

Recomendation: Weakly in favor (There are some studies that show vitamin D may be able to help treat symptoms of Anorexia Nervosa. More studies are needed)

Grade of Evidence: Low level of evidence

Chronic Renal Failure [11, 12, 13, 14]:

Recommendation: Strongly in favor

Grade of Evidence: Moderate level of evidence

Cystic Fibrosis [15, 16, 17]:

Recommendation: Weakly in favor (Early studies show vitamin D may be beneficial for those with CF. More studies needed)

Grade of Evidence: Low level of evidence

Familial Adenomatous Polyposis [1, 5, 7]:

Recommendation: Weakly in favor (Observational studies show that a higher intake of Vitamin D may help lower the risk of getting Familial Adenomatous Polyposis. However, clinical trials need to be completed to provide more reliable evidence.)

Grade of Evidence: Low level of evidence

Osteoporosis [1, 5, 7]:

Recommendation: Strongly in favor (Vitamin D may help to prevent osteoporosis in older people )

Grade of Evidence: High level of evidence

Prostate Cancer [1, 4, 5, 6, 7]:

Recommendation: Weakly in favor (Studies have shown that a higher intake of Vitamin D may help to treat symptoms of bone pain in patients with prostate cancer. However, these results are not fully reliable, and more studies are needed)

Grade of Evidence: Low level of evidence

Psoriasis [1, 5, 7]:

Recommendation: Strongly in favor (Studies have shown that a Vitamin D derivative may be effective in reducing the symptoms of psoriasis)

Grade of Evidence: High level of evidence

Osteoporosis [1, 5, 7]:

Recommendation: Strongly in favor (Studies have shown that a higher intake of vitamin D can reduce the risk of hip fractures among older people following falls. However these studies have had conflicting results, and more studies are needed.)

Grade of Evidence: High level of evidence

Colorectal Cancer [1, 4, 5, 6, 7]:

Recommendation: Weakly in favor (Studies have shown that a higher intake of Vitamin D may help to treat symptoms of bone pain in patients with colorectal cancer. However, these results are not fully reliable, and more studies are needed)

Grade of Evidence: Low level of evidence

* www.gradeworkinggroup.org

References:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

2. http://onlinelibrary.wiley.com/o/cochrane/clsysrev/articles/CD006164/frame.html rickets

3. http://www.ncbi.nlm.nih.gov/pubmed/10824056 rickets

4. http://informahealthcare.com/doi/abs/10.1185/030079908X253519 cancer

5. http://www.ncbi.nlm.nih.gov/pubmed/17556697

6. http://www.ncbi.nlm.nih.gov/pubmed/18065602 cancer

7. http://www.nlm.nih.gov/medlineplus/vitamind.html

8. http://www.ncbi.nlm.nih.gov/pubmed/21632810

9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199303/

10. http://jcp.bmj.com/content/41/2/195

11. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280034/

12. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878736/

13. http://www.ncbi.nlm.nih.gov/pubmed/17293681/

14. http://www.ncbi.nlm.nih.gov/pubmed/15577113

15. http://www.ncbi.nlm.nih.gov/pubmed/24823922

16. http://www.hindawi.com/journals/ije/2010/218691/

17. http://www.ncbi.nlm.nih.gov/pubmed/22513949

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