St Johns Wort (Goatweed, Tipton Weed, Hypericum Perforatum)

Kidney Failure [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat kidney disease)

Grade of Evidence: Low quality of evidence

Subclinical Hypothyroidism [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat hypothyroidism)

Grade of Evidence: Low quality of evidence

Agoraphobia [1]:

Recommendation: No recommendation (There is insufficient evidence to support claims that St Johns Wort helps to treat social phobias. There are currently studies being done to further research these claims)

Grade of Evidence: Very low quality of evidence

Anxiety [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat Anxiety.)

Grade of Evidence: Low quality of evidence

Attention Deficit Hyperactivity Disorder [1, 2]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat ADHD)

Grade of Evidence: Low quality of evidence

Bronchitis [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat bronchitis)

Grade of Evidence: Low quality of evidence

Depression [1, 3, 4, 5, 6, 7, 8, 9, 10]:

Recommendation: Weakly in favor (Clinical trials have shown that St Johns Wort is very effective in the treatment of mild to moderate depression. Studies done with regards to severe depression have yielded mixed results. More studies are needed.)

Grade of Evidence: Low quality of evidence

Generalized Anxiety Disorder [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat Anxiety)

Grade of Evidence: Low quality of evidence

Hemorrhoids [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat hemorrhoids)

Grade of Evidence: Low quality of evidence

Insomnia [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat insomnia)

Grade of Evidence: Low quality of evidence

Malaria [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat malaria)

Grade of Evidence: Low quality of evidence

Migraine [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat migraine)

Grade of Evidence: Low quality of evidence

Mite Bites [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat mite bites)

Grade of Evidence: Low quality of evidence

Obsessive Compulsive Disorder [1]:

Recommendation: No recommendation (There is insufficient evidence to support claims that St Johns Wort helps to treat OCD. There are currently studies being done to further research these claims.)

Grade of Evidence: Very low quality of evidence

Polycystic Kidney Disease [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat kidney disease)

Grade of Evidence: Low quality of evidence

Scorpion Stings [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat scorpion stings)

Grade of Evidence: Low quality of evidence

Adjustment Sleep Disorder [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat sleep disorder)

Grade of Evidence: Low quality of evidence

Psychological Insomnia [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat insomnia)

Grade of Evidence: Low quality of evidence

Anxiety Disorder [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat Anxiety)

Grade of Evidence: Low quality of evidence

Black Widow Spider Bite [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat spider bites)

Grade of Evidence: Low quality of evidence

Nocturnal Enuresis [1]:

Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat nocturnal enuresis)

Grade of Evidence: Low quality of evidence

Major Depressive Disorder [1, 3, 4, 5, 6, 7, 8, 9, 10]:

Recommendation: No recommendation (Clinical trials have shown that St Johns Wort is very effective in the treatment of mild to moderate depression. Studies done with regards to severe depression have yielded mixed results. More studies are needed.)

Grade of Evidence: Moderate quality of evidence

Public Discussion